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长距离三级相互作用在限制Tetrahymena组I ribozyme动态中的作用

Xuesong Shi1, Namita Bisaria, Tara L Benz-Moy

  • 1Department of Biochemistry, ‡Department of Chemistry, §Department of Chemical Engineering, ∥Department of Physics, Stanford University , Stanford, California 94305, United States.

Journal of the American Chemical Society
|April 18, 2014
PubMed
概括

突变的长距离接触在Tetrahymena组I ribozyme影响基质螺旋动力学和催化活性. 值得注意的是,活动与螺旋动力学有很强的相关性,揭示了RNA折叠和功能的独特机制.

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