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自然内部乳腺至冠状动脉旁路的功能及其对心肌缺血的作用

Michael Stoller¹, Stefano F de Marchi¹, Christian Seiler²

¹From the Department of Cardiology, University Hospital, Bern, Switzerland.

|April 19, 2014

概括

自然发生的内部乳腺动脉旁路提供了一个功能性的,减少缺血的血液供应到心脏. 这种心脏外供应是通过ipsilateral而不是 contralateral通道有效的,改善心肌输液.

科学领域:

心血管研究研究心血管研究
冠状动脉疾病冠状动脉疾病
心肌缺血是什么意思心肌缺血是什么意思

背景情况:

自然内部乳腺动脉 (IMA) 对冠状动脉旁路的功能意义尚不清楚.
它们对减少心肌缺血的确切影响尚未得到充分量化.

研究的目的:

为了研究自然内部乳腺动脉 (IMA) 绕道的功能作用.
量化评估这些绕道对心肌缺血的作用.

主要方法:

附带流量指数 (CFI) 在冠状动脉气球阻塞期间测量.
与同时发生内乳动脉 (IMA) 堵塞的情况和没有同时发生内乳动脉堵塞的情况进行了CFI比较.
宫内心电图ST段的升高也得到了定量评估.

主要成果:

当内部乳腺动脉 (IMA) 被堵塞时,观察到附带流量指数 (CFI) 的显著增加 (0.110±0.074对比0.096±0.072,P<0.0001).
最明显和一致的CFI增加发生在ipsilateral阻塞 (左侧IMA与LAD,右侧IMA与RCA) 期间.
在ipsilateral IMA封闭期间,ST段的升高显著减少,这表明缺血减少.

结论:

自然的内部乳腺动脉 (IMA) 绕道提供了一个功能性的心脏外血液供应.
这种供应有效地通过ipsilateral通道减少心肌缺血.
反侧或非双侧IMA连接没有显示出显著的缺血减少效应.

关键词:

抵押品的流通担保.冠状动脉循环的冠状动脉循环乳腺动脉乳腺动脉胸前动脉胸前动脉胸前动脉

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