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Updated: Mar 29, 2026

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
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治疗针对BET原蛋白蛋白在割抵抗性前列腺癌中的治疗向

Irfan A Asangani1, Vijaya L Dommeti2, Xiaoju Wang1

  • 11] Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA [2] Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.

Nature
|April 25, 2014
PubMed
概括

像JQ1这样的基因和外基因 (BET) 抑制剂在治疗晚期前列腺癌方面表现有前途. 这些抑制剂向BRD4,破坏雄激素受体信号传递,并为割抵抗性前列腺癌提供一种新的表观遗传方法.

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