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相关概念视频

Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

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The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
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Oogenesis02:07

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In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
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Ovaries01:26

Ovaries

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The ovaries are roughly the size of almonds and measure approximately 2 to 3 centimeters in length. These paired structures are situated within the pelvic region and are anchored by the mesovarium—a peritoneal extension that also connects them to the wider structure of the broad ligament. The support system extends to the suspensory ligament, housing blood and lymphatic vessels. In addition, the ovarian ligament tethers the ovaries to the uterus.
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The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle...
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Cancer02:18

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Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
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Cells and tissues must meticulously coordinate their activities for the normal functioning of the human body. Therefore, they exhibit socially responsible behavior - resting, growing, dividing, differentiating, or dying - for the organism’s benefit. Cancer arises when cells divide uncontrollably and invade other tissues or organs.
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卵巢癌是发生在卵巢中的癌症.

Gordon C Jayson1, Elise C Kohn2, Henry C Kitchener3

  • 1Institute of Cancer Studies, Christie Hospital and University of Manchester, Wilmslow Road, Withington, Manchester, UK.

Lancet (London, England)
|April 29, 2014
PubMed
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卵巢上皮癌是妇科癌症死亡的主要原因,通常呈现于晚期. 虽然存在标准治疗方法,但复发性疾病和化学抗药性是重大挑战,需要针对性治疗和查的研究.

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科学领域:

  • 妇科瘤学 妇科瘤学
  • 癌症生物学 癌症生物学

背景情况:

  • 表皮卵巢癌是妇科癌症中最常见的死亡原因.
  • 这种疾病通常影响绝经后的妇女,通常在晚期 (FIGO III阶段) 诊断出来.
  • 标准治疗包括手术和基于的化疗,在早期是治愈的,但在复发性疾病中面临挑战.

研究的目的:

  • 审查当前对上皮卵巢癌的理解,包括其表现,标准治疗和挑战.
  • 探索新兴的向治疗方法和早期检测查尚未证明的有效性.

主要方法:

  • 关于上皮卵巢癌流行病学,临床表现和治疗结果的文献综述.
  • 讨论标准的手术和化疗方法.
  • 探索新的向疗法,包括抗血管原药和多 (ADP-ribose) 聚合酶抑制剂.
  • 对卵巢癌查现状和未来前景的评估.

主要成果:

  • 先进阶段的上皮卵巢癌经常复发,导致化学抵抗和高死亡率,主要是由于肠道阻塞.
  • 虽然基于的化疗可以控制多年的响应性疾病,但大多数高级病例会出现复发.
  • 向治疗和改进的查方法有望提高患者的生存率和早期检测.

结论:

  • 表皮卵巢癌仍然是一个重大的健康挑战,特别是在晚期,由于复发和化学抵抗.
  • 针对性治疗的进一步研究和查协议的验证对于改善结果至关重要.
  • 需要有效的管理策略来打击与这种疾病相关的高死亡率.