卵巢癌是发生在卵巢中的癌症
Gordon C Jayson1, Elise C Kohn2, Henry C Kitchener3
1Institute of Cancer Studies, Christie Hospital and University of Manchester, Wilmslow Road, Withington, Manchester, UK.
Lancet (London, England)
|April 29, 2014
概括
卵巢上皮癌是妇科癌症死亡的主要原因,通常呈现于晚期. 虽然存在标准治疗方法,但复发性疾病和化学抗药性是重大挑战,需要针对性治疗和查的研究.
科学领域:
- 妇科瘤学 妇科瘤学
- 癌症生物学 癌症生物学
背景情况:
- 表皮卵巢癌是妇科癌症中最常见的死亡原因.
- 这种疾病通常影响绝经后的妇女,通常在晚期 (FIGO III阶段) 诊断出来.
- 标准治疗包括手术和基于的化疗,在早期是治愈的,但在复发性疾病中面临挑战.
研究的目的:
- 审查当前对上皮卵巢癌的理解,包括其表现,标准治疗和挑战.
- 探索新兴的向治疗方法和早期检测查尚未证明的有效性.
主要方法:
- 关于上皮卵巢癌流行病学,临床表现和治疗结果的文献综述.
- 讨论标准的手术和化疗方法.
- 探索新的向疗法,包括抗血管原药和多 (ADP-ribose) 聚合酶抑制剂.
- 对卵巢癌查现状和未来前景的评估.
主要成果:
- 先进阶段的上皮卵巢癌经常复发,导致化学抵抗和高死亡率,主要是由于肠道阻塞.
- 虽然基于的化疗可以控制多年的响应性疾病,但大多数高级病例会出现复发.
- 向治疗和改进的查方法有望提高患者的生存率和早期检测.
结论:
- 表皮卵巢癌仍然是一个重大的健康挑战,特别是在晚期,由于复发和化学抵抗.
- 针对性治疗的进一步研究和查协议的验证对于改善结果至关重要.
- 需要有效的管理策略来打击与这种疾病相关的高死亡率.
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