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Updated: May 8, 2026

Isolation of Labile Multi-protein Complexes by in vivo Controlled Cellular Cross-Linking and Immuno-magnetic Affinity Chromatography
10:50

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Published on: March 10, 2010

在压力期间,展开的蛋白质反应控制了血液构造干细胞池的完整性

Peter van Galen1, Antonija Kreso1, Nathan Mbong1

  • 11] Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario M5G 2M9, Canada [2] Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

Nature
|April 30, 2014
PubMed
概括

面对压力的人类造血干细胞 (HSC) 通过展开的蛋白质反应 (UPR) 经历了亡. 增强蛋白质折叠改善HSC功能,防止受损的干细胞的传播.

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