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Updated: May 4, 2026

Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens
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Using X-ray Crystallography, Biophysics, and Functional Assays to Determine the Mechanisms Governing T-cell Receptor Recognition of Cancer Antigens

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自免疫T细胞:对正常和变异性表位的免疫识别和基于的治疗

J L Urban1, S J Horvath, L Hood

  • 1Division of Biology, California Institute of Technology, Pasadena 91125.

Cell
|October 20, 1989
PubMed
概括

研究人员研究了小鼠对髓基本蛋白 (MBP) 的T辅助细胞反应,以了解实验性自身免疫脑炎 (EAE). 他们发现了对T细胞识别至关重要的特定区,并开发了阻断EAE诱导的类似物.

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