学前喘的诊断,管理和预后
Francine M Ducharme1, Sze M Tse2, Bhupendrasinh Chauhan3
1Clinical Research and Knowledge Transfer on Childhood Asthma Unit, Research Centre, Sainte-Justine University Health Centre, Montreal, QC, Canada; Department of Paediatrics, University of Montreal, Montreal, QC, Canada; Department of Social and Preventive Medicine, University of Montreal, Montreal, QC, Canada.
Lancet (London, England)
|May 6, 2014
概括
幼儿园喘息是一个重大的健康挑战,长期影响肺功能. 早期干预和经过验证的治疗方法对于治疗幼儿这种疾病至关重要.
科学领域:
- 儿科肺病学 儿科肺病学
- 呼吸系统医学 呼吸系统医学
- 儿童健康 儿童健康
背景情况:
- 与老年人相比,学前喘息 presents一个诊断挑战和高医疗负担.
- 现有的表型分类缺乏用于指导治疗决策的验证.
- 遗传,产前和产后因素与学前喘息有关,有可能导致持续的肺功能缺陷.
研究的目的:
- 审查目前对学前喘的理解,包括风险因素,诊断挑战和治疗方法.
- 要突出学前喘对肺功能的长期影响.
- 确定研究重点,以改善学龄前喘息的结果.
主要方法:
- 关于学龄前喘息的队列研究和临床试验的审查.
- 风险因素,诊断标准和治疗疗效的分析.
- 有关短期和长期结果的证据综合.
主要成果:
- 学前喘与从幼儿到成年期持续的肺功能缺陷有关.
- 每天吸入的皮质类固醇对有间歇症状或亚托皮的复发性喘息有效.
- 间歇性高剂量吸入性皮质类固醇对中度至重度的病毒引起的喘息没有中间症状有好处.
结论:
- 学前喘需要专注的研究,以进行有效的干预措施.
- 需要有效的诊断和治疗策略来解决这种情况.
- 早期治疗可能会减轻长期的呼吸系统损伤.
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