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Updated: Dec 5, 2025

Sensitive Measurement of Mitophagy by Flow Cytometry Using the pH-dependent Fluorescent Reporter mt-Keima
09:13

Sensitive Measurement of Mitophagy by Flow Cytometry Using the pH-dependent Fluorescent Reporter mt-Keima

Published on: August 12, 2018

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在XPA中通过PARP-1过活化和NAD ((+) /SIRT1减少的缺陷线粒

Evandro Fei Fang1, Morten Scheibye-Knudsen1, Lear E Brace2

  • 1Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, MD 21224, USA.

Cell
|May 13, 2014
PubMed
概括

在Xeroderma pigmentosum群A (XPA) 中,线粒体功能障碍与DNA修复缺陷有关. 恢复NAD+水平或抑制PARP-1可以改善线粒体健康和寿命.

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In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice08:40

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Time-Lapse Video Microscopy for Assessment of EYFP-Parkin Aggregation as a Marker for Cellular Mitophagy09:29

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