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使用小分子微阵列识别生物活性,HIV TARRNA结合的小分子

Joanna Sztuba-Solinska1, Shilpa R Shenoy, Peter Gareiss

  • 1HIV Drug Resistance Program, National Cancer Institute , Frederick, Maryland, United States .

Journal of the American Chemical Society
|May 14, 2014
PubMed
概括

研究人员发现了一种新的小分子,可以选择性地与HIV TAR RNA发针结合,提供了一种新的治疗策略. 这种化合物可以抑制艾滋病毒的复制,而不会造成广泛的结构破坏或显著的毒性.

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