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Updated: Apr 29, 2026

Comparative Strategies for Ubiquitination Detection in Mammalian Cell Lysates Using SMAD2/SMURF2 as a Model
09:00

Comparative Strategies for Ubiquitination Detection in Mammalian Cell Lysates Using SMAD2/SMURF2 as a Model

Published on: April 17, 2026

332

SMYD3将MAP3K2的氨酸甲基化与Ras驱动的癌症联系起来

Pawel K Mazur1, Nicolas Reynoird2, Purvesh Khatri3

  • 11] Department of Pediatrics, Stanford University School of Medicine, California 94305, USA [2] Department of Genetics, Stanford University School of Medicine, California 94305, USA [3].

Nature
|May 23, 2014
PubMed
概括

通过SMYD3 (含有蛋白3的SET和MYND域) 的氨酸甲基化通过激活MAP激酶信号来促进Ras驱动的癌症. 抑制SMYD3的催化活性会阻止瘤的发展,提供一种潜在的治疗策略.

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