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TRPV1疼痛受体通过神经信号传递来调节寿命和新陈代谢

Céline E Riera1, Mark O Huising2, Patricia Follett3

  • 1Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA; The Glenn Center for Aging Research, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

Cell
|May 27, 2014
PubMed
概括

缺乏疼痛受体 (TRPV1) 的小鼠寿命更长,并保持年轻的新陈代谢. 这种寿命与降低CGRP有关,改善胰岛素分泌和代谢健康,表明疼痛受体和CGRP通路影响衰老.

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