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Optical Tweezers to Study RNA-Protein Interactions in Translation Regulation
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转移RNA模拟和形态塑性由病毒RNA的结构基础

Timothy M Colussi1, David A Costantino2, John A Hammond3

  • 11] Department of Biochemistry and Molecular Genetics, University of Colorado Denver School of Medicine, Aurora, Colorado 80045, USA [2] Howard Hughes Medical Institute, University of Colorado Denver School of Medicine, Aurora, Colorado 80045, USA [3] Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, USA (T.M.C.); Department of Integrative Structural and Computational Biology, Scripps Research Institute, La Jolla, California 92037, USA (J.A.H.).

Nature
|June 10, 2014
PubMed
概括

黄马赛克病毒 (TYMV) 类似tRNA结构 (TLS) 的RNA具有晶体结构,揭示了其双面性质. 这种RNA模仿tRNA在一张脸上进行氨基化,并在不同的脸上实现其他功能,从而解释了它的多功能性.

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