累积辐射暴露和心脏病儿童癌症风险估计
Jason N Johnson1, Christoph P Hornik1, Jennifer S Li1
1From the Division of Pediatric Cardiology (J.N.J., C.P.H., J.S.L., K.D.H.) and Division of Radiology (T. T. Y., R.E.R., D.P.F.), Department of Pediatrics, Duke University Medical Center, Durham, NC; and Duke Clinical Research Institute, Durham, NC (J.S.L., D.K.B., K.D.H.).
Circulation
|June 11, 2014
概括
患有心脏病的儿童经常接受放射成像. 这项研究发现,整体辐射暴露很低,但某些群体面临更高的风险,需要降低剂量,特别是高暴露成像测试.
科学领域:
- 儿童心脏病学 儿童心脏病学
- 医疗成像医学成像
- 辐射瘤学 辐射瘤学
背景情况:
- 患有心脏病的儿童经常使用电离辐射进行成像检查.
- 在这个人群中,累积辐射暴露和相关癌症风险的数据有限.
研究的目的:
- 评估心脏病儿童所有检查中的累积有效辐射剂量.
- 估计与这种暴露相关的终身可归因的癌症风险.
主要方法:
- 研究了一组337名儿童 (≤6岁),他们在2005-2010年间接受了心脏手术.
- 累计有效剂量 (mSv) 由13932次辐射检查计算出来.
- 使用电离辐射生物影响委员会VII方法估计了终身可归因的癌症风险.
主要成果:
- 传统的X光片占了92%的检查,但心脏导管和CT扫描占累计剂量的81%.
- 平均累积有效剂量为2.7mSv,平均终身癌症风险为0.07%.
- 癌症风险因手术复杂性而异,女性每有效剂量单位的癌症风险更高.
结论:
- 儿科心脏病患者的辐射暴露通常很低.
- 特定的患者队伍接受大量的辐射剂量,需要注意.
- 限制辐射剂量,特别是从高暴露成像方式,对于降低癌症风险至关重要.
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