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Updated: Apr 27, 2026

In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice
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Published on: November 22, 2017

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糖尿病易感性基因Clec16a调节了线粒的发生

Scott A Soleimanpour1, Aditi Gupta2, Marina Bakay3

  • 1Division of Endocrinology, Diabetes and Metabolism, Department of Medicine and the Institute for Diabetes, Obesity and Metabolism of the University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA; Division of Metabolism, Endocrinology & Diabetes and Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48105, USA.

Cell
|June 21, 2014
PubMed
概括

克莱克16a蛋白对胰腺β细胞功能和通过调节线粒细胞衰变来预防糖尿病至关重要. 失去Clec16a会损害胰岛素分泌和线粒体健康,影响葡萄糖代谢.

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