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Updated: Apr 27, 2026

Biochemical Reconstitution of Steroid Receptor•Hsp90 Protein Complexes and Reactivation of Ligand Binding
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Published on: September 21, 2011

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葡萄糖皮质体受体功能由Hsp90和Hsp70伴侣循环的协调作用调节

Elaine Kirschke1, Devrishi Goswami2, Daniel Southworth1

  • 1Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA 94158, USA.

Cell
|June 21, 2014
PubMed
概括

分子伴侣Hsp70和Hsp90调节葡萄糖皮质体受体 (GR) 功能. Hsp70使GR失活,而Hsp90,与cochaperones一起,恢复其结合结合能力和稳定性.

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