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在β-catenin破坏复合体中YAP/TAZ的结合协调了Wnt反应

Luca Azzolin1, Tito Panciera1, Sandra Soligo1

  • 1Department of Molecular Medicine, University of Padua School of Medicine, viale Colombo 3, 35126 Padua, Italy.

Cell
|July 1, 2014
PubMed
概括

河马通路蛋白YAP/TAZ与β-catenin破坏复合体集成,调节Wnt信号传输. 它们的释放激活了Wnt/YAP/TAZ效应,对器官大小和再生至关重要.

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