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一个甲基转移酶启动了teleocidin B生物合成中的烯循环

Takayoshi Awakawa1, Lihan Zhang, Toshiyuki Wakimoto

  • 1Graduate School of Pharmaceutical Sciences, The University of Tokyo , Bunkyo-ku, Tokyo 113-0033, Japan.

Journal of the American Chemical Society
|July 4, 2014
PubMed
概括

研究人员确定了teleocidin B生物合成的基因,这是一种蛋白质激酶C激活剂. 一种新型的甲基转移酶 (tleD) 通过阴离子形成触发了类环的闭合,这是这种途径的首次.

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