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Updated: Apr 27, 2026

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人类多能干细胞被一种海洋天然产品衍生物选择性消除

Ting-Fang Kuo1, Di Mao, Nao Hirata

  • 1Institute for Integrated Cell-Material Sciences (WPI-iCeMS), Kyoto University , Kyoto 606-8501, Japan.

Journal of the American Chemical Society
|July 4, 2014
PubMed
概括

科学家们发现了一种可以杀死人类多能干细胞的化合物,这是更安全的干细胞治疗的关键一步. 这一发现解决了治疗中从未分化的细胞中瘤形成的风险.

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Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
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Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic...
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