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葡萄糖通过O-GlcNAc转移酶的米尔顿修饰来调节线粒体运动

Gulcin Pekkurnaz1, Jonathan C Trinidad2, Xinnan Wang3

  • 1The F.M. Kirby Neurobiology Center, Boston Children's Hospital and Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA.

Cell
|July 5, 2014
PubMed
概括

神经元根据营养的可用性来调节线粒体的运动. 酶O-GlcNAc转移酶 (OGT) 修改了米尔顿蛋白,在葡萄糖丰富时降低了线粒体的运动性.

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