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类固醇/甲状腺激素受体的基因特异性的决定因素

K Umesono1, R M Evans

  • 1Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, California 92037.

Cell
|June 30, 1989
PubMed
概括

研究人员改变了激素受体,改变了它们的DNA结合特异性. 一些氨基酸变化将葡萄糖皮质体受体转化为雌激素或甲状腺激素受体,揭示了关键的结构决定因素.

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