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Updated: Apr 27, 2026

Adenoviral Transduction of Naive CD4 T Cells to Study Treg Differentiation
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在大象鱼中的TH2和Treg候选基因

Johannes M Dijkstra1

  • 1Institute for Comprehensive Medical Science, Fujita Health University, Dengaku-gakubo 1-98, 470-1192 Toyoake, Aichi, Japan.

Nature
|July 11, 2014
PubMed
概括

No abstract available in PubMed .

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When T cells with CD4 markers are activated, they give rise to two types of effector cells: helper T cells and regulatory T cells. Meanwhile, T cells with CD8 markers differentiate into effector cytotoxic T cells. The differentiation of CD4 T cells into helper T cell subsets, such as Th1, Th2, and Th17 cells, is dependent on the antigen type, antigen-presenting cell, and regulatory cytokines.
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
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