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相关概念视频

Evolution of New Traits in Microbes01:24

Evolution of New Traits in Microbes

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Microorganisms evolve rapidly due to their large population sizes and short generation times, often exhibiting measurable changes within days under laboratory conditions. Natural selection acts on standing genetic variation, enabling the retention and amplification of beneficial traits that confer fitness advantages in changing environments.Adaptive Pigment Regulation in RhodobacterIn Rhodobacter, a genus of purple non-sulfur bacteria, light-harvesting pigments such as bacteriochlorophyll and...
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Limits to Natural Selection01:38

Limits to Natural Selection

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Organisms that are well-adapted to their environment are more likely to survive and reproduce. However, natural selection does not lead to perfectly adapted organisms. Several factors constrain natural selection.
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Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

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The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
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Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

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Hardy-Weinberg Principle01:49

Hardy-Weinberg Principle

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Diploid organisms have two alleles of each gene, one from each parent, in their somatic cells. Therefore, each individual contributes two alleles to the gene pool of the population. The gene pool of a population is the sum of every allele of all genes within that population and has some degree of variation. Genetic variation is typically expressed as a relative frequency, which is the percentage of the total population that has a given allele, genotype or phenotype.
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The Evidence for Evolution02:55

The Evidence for Evolution

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Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.
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相关实验视频

Updated: Apr 26, 2026

Solid Plate-based Dietary Restriction in Caenorhabditis elegans
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在Lamarckck的卡路里限制.

Eugene V Koonin1

  • 1National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA.

Cell
|July 19, 2014
PubMed
概括

表观遗传,以前见过外源小干扰 (si) RNA,现在显示为饥饿诱导的基因沉默. 这种获得的特征延长了长寿到第三代,这表明拉马克遗传是一种关键的进化机制.

科学领域:

  • 表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.
  • 进化生物学 进化生物学
  • 分子生物学分子生物学

背景情况:

  • 通过小干扰 (si) RNA的表观遗传在动物模型中得到了记录.
  • 获得的特征通常不会通过遗传传给后代.

研究的目的:

  • 研究获得的表观遗传变化的遗传性.
  • 为了确定环境诱导的基因沉默是否可以在几代人之间继承.

主要方法:

  • 在动物模型中通过饥饿诱导基因沉默.
  • 分析基因表达模式和几代人间的表观遗传修饰.
  • 利用内源性小干扰RNAs (siRNAs) 作为遗传的媒介.

主要成果:

  • 证明了饥饿诱导的基因沉默模式的遗传.
  • 观察到第三代后代的寿命增加.
  • 展示了内源性siRNAs在传输获得的表观遗传信息中的作用.

结论:

  • 获得性特征的表观遗传是可能的,包括那些由饥饿等环境因素引起的特征.
  • 表明获得特征的拉马尔克式遗传是一种重要的进化现象.

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Quantification of Information Encoded by Gene Expression Levels During Lifespan Modulation Under Broad-range Dietary Restriction in C. elegans
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相关实验视频

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Quantification of Information Encoded by Gene Expression Levels During Lifespan Modulation Under Broad-range Dietary Restriction in C. elegans
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  • 突出了内源性siRNAs在调解跨代表观遗传中的作用.