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癌症中的PVT1依赖与MYC副本数量的增加

Yuen-Yi Tseng1, Branden S Moriarity2, Wuming Gong3

  • 1Department of Genetics, Cell Biology and Development, University of Minnesota, Twin Cities, Minneapolis, Minnesota 55455, USA.

Nature
|July 22, 2014
PubMed
概括

8q24.21区域的增加,包括MYC瘤基因和PVT1长非编码RNA,促进癌症. PVT1 RNA对于高MYC蛋白水平至关重要,提供了一个新的治疗点.

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