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Updated: Apr 26, 2026

Transmembrane Domain Oligomerization Propensity determined by ToxR Assay
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Published on: May 26, 2011

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超膜螺旋6的位置决定了受体G蛋白合特异性

Alexander S Rose1, Matthias Elgeti, Ulrich Zachariae

  • 1Institut für Medizinische Physik und Biophysik, ‡AG ProteiInformatics, and #AG Protein X-ray Crystallography, Charité-Universitätsmedizin Berlin , Charitéplatz 1, 10117 Berlin, Germany.

Journal of the American Chemical Society
|July 22, 2014
PubMed
概括

G蛋白结合受体 (GPCR) 使用不同的构造来结合Gi或G蛋白,从而影响信号特异性. 这项研究揭示了受体结构如何决定G蛋白合选择性.

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