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Updated: Apr 26, 2026

High-throughput Quantitative Real-time RT-PCR Assay for Determining Expression Profiles of Types I and III Interferon Subtypes
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Published on: March 24, 2015

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这是一种炎症. 25-基胆固醇抑制了I型干扰素下游的因特乐金-1驱动的炎症

Andrea Reboldi1, Eric V Dang1, Jeffrey G McDonald2

  • 1Howard Hughes Medical Institute, Department of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA.

Science (New York, N.Y.)
|August 9, 2014
PubMed
概括

I型干扰素 (IFN) 信号通常会抑制炎症. 新的研究表明,氧25-胆固醇 (25-HC) 是这一点的关键,因为缺乏它会导致 IL-1 等炎症性细胞因子的过度产生.

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