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Updated: Apr 25, 2026

Tissue-specific miRNA Expression Profiling in Mouse Heart Sections Using In Situ Hybridization
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Published on: September 15, 2018

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一个长的非编码RNA保护心脏免受病理性缩.

Pei Han1,2, Wei Li1, Chiou-Hong Lin1

  • 1Division of Cardiovascular Medicine, Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305.

Nature
|August 15, 2014
PubMed
概括

最近发现的一种心脏特异性的长非编码RNA,Mhrt,通过抑制染色质重塑剂Brg1.1,来保护成年人的心脏. 失去Mhrt对于心力衰竭的发展至关重要,但恢复它可以防止心脏功能障碍.

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