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结构生物学 结构生物学. 一个由CRISPRRNA引导的监控复合体的晶体结构与一个ssDNA目标结合在一起

Sabin Mulepati1, Annie Héroux2, Scott Bailey3

  • 1Department of Biochemistry and Molecular Biology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.

Science (New York, N.Y.)
|August 16, 2014
PubMed
概括

大肠杆菌中的CRISPR-Cas Cascade复合体与单链DNA标结合. 它的晶体结构显示出一个独特的,绕着带状的RNA-DNA混合结构,这种结构对于功能至关重要.

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