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Updated: Apr 25, 2026

Author Spotlight: Epigenetic Modifications and Metabolic Rewiring as Targets for Cancer Therapy
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转化差异化. 转化差异化. 这是一个非常重要的过程. 连续的质子修饰活动决定了转差异化的稳定性

Steven Zuryn1, Arnaud Ahier1, Manuela Portoso2

  • 1Department of Development and Stem Cells, Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR 7104/INSERM U964, Université de Strasbourg, 67404 Illkirch CU Strasbourg, France.

Science (New York, N.Y.)
|August 16, 2014
PubMed
概括

在C. elegans中,自然细胞重编程涉及JMJD-3.1和Set1.1基因组修饰剂. 这些蛋白质通过协调不同阶段的表观遗传变化来确保强大的转基因差异化 (Td),并行于体外重编程.

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