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Updated: Apr 25, 2026

In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol
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In Vitro Differentiation of Human CD4+FOXP3+ Induced Regulatory T Cells (iTregs) from Naïve CD4+ T Cells Using a TGF-β-containing Protocol

Published on: December 30, 2016

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一个Foxp3 cis元素在保护调节性T细胞身份的功能

Xudong Li1, Yuqiong Liang1, Mathias LeBlanc1

  • 1Nomis Foundation Laboratories for Immunobiology and Microbial Pathogenesis, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

Cell
|August 16, 2014
PubMed
概括

一个特定的DNA元素,保存的非编码序列2 (CNS2),保护调节性T (Treg) 细胞的身份. 这种表观遗传机制维持免疫平衡,并通过感知环境线索来预防自身免疫性疾病.

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