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MicroRNA Amplification and Recognition through Locked-nucleic-acid In situ Hybridization as a Novel Detection and Quantification Method
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通过DDX17的茎环识别促进了miRNA处理和抗病毒防御.

Ryan H Moy1, Brian S Cole2, Ari Yasunaga1

  • 1Department of Microbiology, Penn Genome Frontiers Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.

Cell
|August 16, 2014
PubMed
概括

死亡盒螺旋酶DDX17限制了裂谷热病毒 (RVFV) 的感染. 这种免疫作用是保留和独立于干扰素,涉及DDX17与病毒RNA和宿主微RNA前体结合.

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