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Updated: Jul 18, 2026

Inducible and Reversible Dominant-negative (DN) Protein Inhibition
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在其生物特性方面,Jun-B与c-Jun不同,并且是c-Jun的负调节器

R Chiu1, P Angel, M Karin

  • 1Department of Pharmacology, School of Medicine, University of California, San Diego, La Jolla 92093.

Cell
|December 22, 1989
PubMed
概括

家族蛋白c-Jun和Jun-B表现出不同的基因激活能力. 虽然c-Jun有效地激活单个TPA反应元素 (TRE) 促进体,但Jun-B需要多个TRE和合作相互作用来激活,扩大Jun蛋白调节作用.

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