基于植入物的多参数心力衰竭患者远程监测 (IN-TIME):一种随机对照试验
Gerhard Hindricks1, Milos Taborsky2, Michael Glikson3
1Herzzentrum Leipzig, Leipzig, Germany.
Lancet (London, England)
|August 19, 2014
概括
每日基于植入物的远程监测显著改善了心力衰竭患者的临床结果. 这种技术是可行的,并建议用于临床实践,以提高患者的护理.
科学领域:
- 心脏病学 心脏病学
- 医疗技术 医疗技术 医学技术
- 临床试验 临床试验
背景情况:
- 在心力衰竭患者中,可植入式心脏转换器-除器 (ICD) 和CRT-D与远程监测的使用越来越多.
- 关于早期发现心力衰竭恶化的有效性证据有限,通过远程监测进行预防性干预.
研究的目的:
- 调查自动,每日,基于植入物的多参数远程监测在改善心力衰竭患者的治疗结果方面的有效性.
- 评估远程监控在心力衰竭管理中的预防性干预的可行性.
主要方法:
- 在澳大利亚,欧洲和以色列36个中心进行随机对照试验 (IN-TIME).
- 招募了患有慢性心力衰竭的患者 (NYHA II-III类,EF ≤35%) 与ICD或CRT-Ds.
- 每天远程监控加上标准护理与仅仅标准护理在一年内进行比较.
主要成果:
- 664名患者被随机分配 (333名远程监控,331名对照).
- 远程监控组显示,复合得分恶化率明显较低 (18.9%与27.2%,p=0.013).
- 在远程监控组中发生的死亡人数较少 (10对27).
结论:
- 自动,每日,基于植入物的远程监测显著改善了心力衰竭患者的临床结果.
- 远程监测是临床实践中管理心力衰竭的可行和有效工具.
- 支持远程监控的常规使用,以积极管理心力衰竭.
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