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RIPK1通过保护上皮质免受亡的作用来确保肠道平衡

Nozomi Takahashi1, Lars Vereecke1, Mathieu J M Bertrand1

  • 11] VIB Inflammation Research Center, Technologiepark 927, B-9052 Ghent, Belgium [2] Department of Biomedical Molecular Biology, Ghent University, Technologiepark 927, B-9052 Ghent, Belgium.

Nature
|September 5, 2014
PubMed
概括

受体相互作用蛋白激酶1 (RIPK1) 对于肠上皮细胞 (IEC) 存活至关重要,防止编程细胞死亡和维持肠道平衡. 它的酶独立功能保护肠道内膜免受亡.

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