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Updated: Apr 24, 2026

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes
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Published on: November 1, 2012

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含有s(2) U:A和s(2) U:U基对的RNA复合体的晶体结构研究

Jia Sheng1, Aaron Larsen, Benjamin D Heuberger

  • 1Howard Hughes Medical Institute, Center for Computational and Integrative Biology, and Department of Molecular Biology, Simches Research Center, Massachusetts General Hospital , Boston, Massachusetts 02114, United States.

Journal of the American Chemical Society
|September 5, 2014
PubMed
概括

结构研究显示,2-thio-uridine (s(2) U) 稳定了U:A对,并特别稳定了RNA复杂体中的一个U:U构造,可能是通过硫键. 这提供了对RNA中修饰核基的新见解.

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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids09:04

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RNA Structure01:23

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