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Updated: Apr 24, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
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瘤抑制剂p53的酸化转激活域的扩展串结合模式

Masahiko Okuda1, Yoshifumi Nishimura

  • 1Graduate School of Medical Life Science, Yokohama City University , 1-7-29 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045, Japan.

Journal of the American Chemical Society
|September 13, 2014
PubMed
概括

瘤抑制器p53的交换活化域 (TAD) 具有显著的灵活性. 酸化的p53 TAD2以一种独特的弦状方式与酸化后的螺旋结构不同,结合酸化的p53 TAD2与酸化后的状结构不同.

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