电子药物包装设备和药物坚持:系统审查
Kyle D Checchi1, Krista F Huybrechts1, Jerry Avorn1
1Program on Regulation, Therapeutics, and Law, Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
JAMA
|September 24, 2014
概括
电子药物包装 (EMP) 设备可以改善慢性疾病的药物坚持. 集成到医疗保健中的系统,记录剂量事件,显示出最有希望的结果,尽管需要更多高质量的研究.
科学领域:
- 医疗信息学 医疗信息学
- 药物坚持研究 药物坚持研究
- 数字健康干预措施 数字健康干预措施
背景情况:
- 药物不服药影响了大量患有慢性疾病的患者,如高血压,高脂血症和糖尿病.
- 电子药物包装 (EMP) 设备,旨在监测服药,提供了一个潜在的解决方案,以改善患者的服药.
研究的目的:
- 评估EMP设备在改善药物服药的有效性.
- 识别和描述现有的EMP设备的共同特征.
主要方法:
- 对37项同行评审研究 (32项随机,5项非随机) 进行了系统性审查,涉及4326名患者.
- 这些研究来源于多个数据库 (MEDLINE,EMBASE,PsycINFO,CINAHL等). 在2014年6月之前.
- 偏差评估使用了柯克兰手册;EMP设备特征被定性分析.
主要成果:
- 干预对坚持的影响有所不同,平均坚持差异从-2.9%到+34.0%不等,坚持比例差异从-8.0%到+49.5%.
- 常见的EMP特征包括记录的剂量事件,视听提醒,数字显示,实时监控和遵守反.
- 整合到医疗保健系统中的复杂干预措施和记录剂量事件与遵守改善最为相关.
结论:
- 有各种EMP设备可用,但支持证据有限,研究质量各不相同.
- 整合到护理提供和记录剂量事件的设备显示了最一致的与改善依从性的关联.
- 需要进一步进行高质量的研究,以证实EMP设备的有效性,并优化其组件用于药物不服药.
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