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Updated: May 6, 2026

DNAzyme-dependent Analysis of rRNA 2’-O-Methylation
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探测U2 snRNP的结构和功能,使用由2'-OMe RNA制成的反意义寡核酸

A I Lamond1, B Sproat, U Ryder

  • 1European Molecular Biology Laboratory, Heidelberg, Federal Republic of Germany.

Cell
|July 28, 1989
PubMed
概括

反意义寡核酸揭示了U2小核RNA (snRNA) 域,这些域对拼接至关重要. 掩盖特定的U2 snRNA区域可以抑制结合体组合或mRNA前结合,从而澄清它们在RNA拼接中的作用.

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