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微生物组的饮食调节会影响自身炎症性疾病

John R Lukens1, Prajwal Gurung1, Peter Vogel2

  • 1Department of Immunology, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA.

Nature
|October 3, 2014
PubMed
概括

饮食中的脂肪和胆固醇通过改变肠道微生物组并降低介质蛋白-1β (IL-1β) 生产,保护小鼠免受炎症性骨病的影响. 这涉及Prevotella细菌和caspase-8信号传递.

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