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总合成和确定RAKICIDIN A的绝对配置

Feng Sang1, Dongmei Li, Xiaolong Sun

  • 1College of Pharmacy, State Key Laboratory of Elemento-Organic Chemistry, State Key Laboratory of Medicinal Chemical Biology, Nankai University , Collaborative Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin 300071 P. R. China.

Journal of the American Chemical Society
|October 7, 2014
PubMed
概括

研究人员确定了rakicidin A的立体化学,rakicidin A是一种具有潜在抗癌干细胞活性的循环脱. 总合成证实了它的绝对配置,有助于未来治疗慢性骨髓性白血病的药物开发.

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