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Updated: Apr 22, 2026

Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay
07:10

Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay

Published on: September 14, 2014

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三重体前融合HIV-1 Env的结构和免疫识别

Marie Pancera1, Tongqing Zhou1, Aliaksandr Druz1

  • 1Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA.

Nature
|October 9, 2014
PubMed
概括

研究人员确定了人类免疫缺陷病毒1型 (HIV-1) 包裹 (Env) 尖端在封闭状态下的结构. 这为HIV-1进入机制和用于疫苗开发的抗体识别提供了洞察力.

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Determination of Molecular Structures of HIV Envelope Glycoproteins using Cryo-Electron Tomography and Automated Sub-tomogram Averaging07:29

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Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding10:50

Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding

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Antigens Involved in Adaptive Immunity01:26

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