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Updated: Apr 22, 2026

Metabolic Labeling and Membrane Fractionation for Comparative Proteomic Analysis of Arabidopsis thaliana Suspension Cell Cultures
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来自Methylomicrobium alcaliphilum的整体膜固醇还原酶的结构

Xiaochun Li1, Rita Roberti2, Günter Blobel1

  • 1Laboratory of Cell Biology, Howard Hughes Medical Institute, The Rockefeller University, New York, New York 10065, USA.

Nature
|October 14, 2014
PubMed
概括

我们确定了细菌 Δ(14) - 胆固醇还原酶 (MaSR1) 的晶体结构,揭示了其整体膜结构和机制. 这提供了对与先天性疾病相关的人类固醇减少酶的分子洞察力.

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