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Blocking Lymph Flow by Suturing Afferent Lymphatic Vessels in Mice
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树突细胞控制纤维细胞网状网络的张力和淋巴结扩张

Sophie E Acton1, Aaron J Farrugia2, Jillian L Astarita3

  • 11] Immunobiology Laboratory, Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3LY, UK [2] Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK.

Nature
|October 25, 2014
PubMed
概括

免疫期间的淋巴结扩张依赖于波多普拉宁 (PDPN) 和CLEC-2信号传递. 树突细胞使用CLEC-2来放松纤维细胞网状细胞 (FRC) 中的PDPN,允许淋巴结生长.

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