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Updated: Aug 10, 2026

Genetic Barcoding with Fluorescent Proteins for Multiplexed Applications
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Genetic Barcoding with Fluorescent Proteins for Multiplexed Applications

Published on: April 14, 2015

通过同源重组组合选择以精确的染色体向主导标记物

J R Dorin1, J D Inglis, D J Porteous

  • 1MRC Human Genetics Unit, Western General Hospital, Edinburgh, United Kingdom.

Science (New York, N.Y.)
|March 10, 1989
PubMed
概括

研究人员精确地将neomycin phosphotransferase (neo) 基因定位到人类染色体7上,使用同源重组. 这种基因向策略能够实现精确的基因组突变和潜在的基因功能恢复.

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Maxam-Gilbert Sequencing01:05

Maxam-Gilbert Sequencing

In the same year as the discovery of the Sanger sequencing method, another group of scientists, Allan Maxam and Walter Gilbert, demonstrated their chemical-cleavage method for DNA sequencing. The Maxam-Gilbert method relies on using different chemicals that can cleave the DNA sequence at specific sites, the separation of resulting DNA fragments of variable size using electrophoresis, and deciphering the DNA sequence from the resulting gel bands.
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