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Updated: Apr 20, 2026

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通过TRiC介导的TCAB1折叠,对端粒酶功能的蛋白质静止控制

Adam Freund1, Franklin L Zhong2, Andrew S Venteicher1

  • 1Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA.

Cell
|December 4, 2014
PubMed
概括

沙佩罗宁TRiC通过折叠其辅因子TCAB1.1,对端粒酶功能至关重要. 损坏的TRiC功能会扰乱端粒的维护,导致衰老和先天性皮质障碍.

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