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Updated: Apr 19, 2026

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells
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Published on: January 20, 2019

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B细胞超强增强剂和调控集群招募AID瘤原性活动

Jason Qian1, Qiao Wang2, Marei Dose1

  • 1Genomics and Immunity, NIAMS, NIH, Bethesda, MD 20892, USA.

Cell
|December 9, 2014
PubMed
概括

抗体基因突变体,激活诱导的胺酶 (AID),针对超级增强剂内的瘤基因,而不是随机. 这些3D连接的监管区域合作招募AID,推动瘤发生.

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