治疗急性支气管炎的抗生素
Susan M Smith1, John Smucny2, Tom Fahey1
1HRB Centre for Primary Care Research, Department of General Practice, Royal College of Surgeons in Ireland Medical School, Dublin.
JAMA
|December 24, 2014
概括
治疗急性支气管炎的抗生素可能会略微减少咳持续时间和疾病严重程度,但没有显著的整体临床改善. 抗生素组出现了更多的不良反应,特别是胃肠道问题.
科学领域:
- 一般的做法一般的做法
- 传染性疾病 传染性疾病
- 呼吸系统医学 呼吸系统医学
背景情况:
- 急性支气管炎是一种常见的呼吸道疾病,通常是经验性地管理的.
- 抗生素在治疗急性支气管炎中的作用仍然是临床辩论的主题.
研究的目的:
- 评估诊断患有急性支气管炎的患者的抗生素处方和临床结果之间的关联.
主要方法:
- 一项比较研究评估了接受抗生素与接受安慰剂的急性支气管炎患者的结果.
主要成果:
- 抗生素使用与咳持续时间的适度减少,感觉不好的日子和活动受损有关.
- 在抗生素和安慰剂组之间,在整体临床改善或功能限制方面没有发现显著差异.
- 副作用,特别是胃肠道症状,在抗生素组显著高.
结论:
- 虽然抗生素可以为急性支气管炎提供轻微的症状缓解,但它们不会带来大量的整体临床益处.
- 与急性支气管炎抗生素使用相关的不良事件的风险增加需要仔细考虑.
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