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的新陈代谢. 通过白和谷氨胺对mTORC1的不同调节

Jenna L Jewell1, Young Chul Kim1, Ryan C Russell1

  • 1Department of Pharmacology and Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA.

Science (New York, N.Y.)
|January 9, 2015
PubMed
概括

特定的氨基酸差异性调节细胞生长途径. 氨酸通过Rag GTPases激活mTORC1通路,而谷氨酸则使用一个不同的机制,涉及真空H(+) - 氨酸三酸酶 (v-ATPase) 和ADP-核糖化因子-1 GTPase.

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