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在tRNA转位过程中,核糖体上延长因子G的形状变化

Jinzhong Lin1, Matthieu G Gagnon2, David Bulkley3

  • 1Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT 06520-8114, USA.

Cell
|January 17, 2015
PubMed
概括

延长因子G (EF-G) 在核糖体上移动tRNA和mRNA. 新的结构揭示了紧和延长状态之间的EF-G过渡,解释了tRNA转位,这是一种dityromycin可以阻止的过程.

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