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在下丘脑神经元中,MC4R与Kir7.1的G蛋白独立合

Masoud Ghamari-Langroudi1, Gregory J Digby1, Julien A Sebag1

  • 1Department of Molecular Physiology &Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA.

Nature
|January 21, 2015
PubMed
概括

在下丘脑中,黑色皮质-4受体 (MC4R) 信号调节能量平衡. 新的研究表明,α-MSH和AgRP通过通道Kir7.1调节神经元活动,独立于传统的Gαs通路.

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