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Updated: Apr 18, 2026

Identification of RNAs Engaged in Direct RNA-RNA Interaction with a Long Non-Coding RNA
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一个核糖核酶在RNAi过程中协调siRNA放大和mRNA分裂

Hsin-Yue Tsai1, Chun-Chieh G Chen2, Darryl Conte2

  • 1RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605, USA; Institute of Biological Chemistry, Academia Sinica, Nankang, Taipei 115, Taiwan.

Cell
|January 31, 2015
PubMed
概括

在C. elegans中,RNA干扰 (RNAi) 沉默依赖于RDE-8,这是一个分裂目标信使RNA (mRNA) 的酶. 此外,RDE-8还促进了小干扰RNAs (siRNAs) 的放大,以实现强大的基因沉默.

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